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Delivery

Extraordinary Enstilar® delivery
Extraordinary Enstilar delivery, new psoriasis treatment in a foam spray formulation.

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Once Enstilar® is sprayed onto the skin, the propellants evaporate. This leaves fully dissolved, non-crystalline active ingredients available for skin penetration.1

This is known as supersaturation.1

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In laboratory tests, the active ingredients of Enstilar® remained in this supersaturated state for up to 18 hours after spraying, whereas crystals of active ingredient were detected in ointment formulation.1

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In a skin penetration model, the foam spray formulation of Enstilar® improved drug delivery and enhanced local bioavailability of calcipotriol and betamethasone dipropionate, compared with Dovobet® ointment.2

See this extraordinary
delivery in action
References
  1. Warren R et al. Poster 3825 presented at the 74rd AAD Conference; Washington DC, USA, 4–8 March 2016.
  2. Basse LH et al. J Invest Dermatol 2014; 134: Abstract 192. 44th Annual ESDR Meeting; Denmark, Copenhagen, 10–13 September.

UK/IE MAT-04320 V3
Date of preparation: October 2017